Binding Mode Analyses and Pharmacophore Model Development for Stilbene Derivatives as a Novel and Co...
Binding Mode Analyses and Pharmacophore Model Development for Stilbene Derivatives as a Novel and Competitive Class of α-Glucosidase Inhibitors
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Stilbene urea derivatives as a novel and competitive class of non-glycosidic α-glucosidase inhibitors are effective for the treatment of type II diabetes and obesity. The main purposes of our molecular modeling study are to explore the most suitable binding poses of stilbene derivatives with analyzing the binding affinity differences and finally to...
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Binding Mode Analyses and Pharmacophore Model Development for Stilbene Derivatives as a Novel and Competitive Class of α-Glucosidase Inhibitors
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TN_cdi_plos_journals_1490992538
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1490992538
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0085827