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Growth arrest specific 2 is up-regulated in chronic myeloid leukemia cells and required for their gr...

Growth arrest specific 2 is up-regulated in chronic myeloid leukemia cells and required for their gr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1490992803

Growth arrest specific 2 is up-regulated in chronic myeloid leukemia cells and required for their growth

About this item

Full title

Growth arrest specific 2 is up-regulated in chronic myeloid leukemia cells and required for their growth

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-01, Vol.9 (1), p.e86195-e86195

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Although the generation of BCR-ABL is the molecular hallmark of chronic myeloid leukemia (CML), the comprehensive molecular mechanisms of the disease remain unclear yet. Growth arrest specific 2 (GAS2) regulates multiple cellular functions including cell cycle, apoptosis and calpain activities. In the present study, we found GAS2 was up-regulated i...

Alternative Titles

Full title

Growth arrest specific 2 is up-regulated in chronic myeloid leukemia cells and required for their growth

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1490992803

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1490992803

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0086195

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