Influence of aggregation and route of injection on the biodistribution of mouse serum albumin
Influence of aggregation and route of injection on the biodistribution of mouse serum albumin
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Protein aggregates are a major risk factor for immunogenicity. Until now most studies on aggregate-driven immunogenicity have focused on linking physicochemical features of the aggregates to the formation of anti-drug antibodies. Lacking is however, basic knowledge on the effect of aggregation on the biodistribution and clearance of therapeutic pro...
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Full title
Influence of aggregation and route of injection on the biodistribution of mouse serum albumin
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TN_cdi_plos_journals_1491120412
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1491120412
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0085281
