Prevalence and Evolution of Low Frequency HIV Drug Resistance Mutations Detected by Ultra Deep Seque...
Prevalence and Evolution of Low Frequency HIV Drug Resistance Mutations Detected by Ultra Deep Sequencing in Patients Experiencing First Line Antiretroviral Therapy Failure
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Clinical relevance of low-frequency HIV-1 variants carrying drug resistance associated mutations (DRMs) is still unclear. We aimed to study the prevalence of low-frequency DRMs, detected by Ultra-Deep Sequencing (UDS) before antiretroviral therapy (ART) and at virological failure (VF), in HIV-1 infected patients experiencing VF on first-line ART.
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Prevalence and Evolution of Low Frequency HIV Drug Resistance Mutations Detected by Ultra Deep Sequencing in Patients Experiencing First Line Antiretroviral Therapy Failure
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TN_cdi_plos_journals_1492015175
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1492015175
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0086771
