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IL-4 Suppresses the Responses to TLR7 and TLR9 Stimulation and Increases the Permissiveness to Retro...

IL-4 Suppresses the Responses to TLR7 and TLR9 Stimulation and Increases the Permissiveness to Retro...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1492542210

IL-4 Suppresses the Responses to TLR7 and TLR9 Stimulation and Increases the Permissiveness to Retroviral Infection of Murine Conventional Dendritic Cells

About this item

Full title

IL-4 Suppresses the Responses to TLR7 and TLR9 Stimulation and Increases the Permissiveness to Retroviral Infection of Murine Conventional Dendritic Cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-01, Vol.9 (1), p.e87668-e87668

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

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Scope and Contents

Contents

Th2-inducing pathological conditions such as parasitic diseases increase susceptibility to viral infections through yet unclear mechanisms. We have previously reported that IL-4, a pivotal Th2 cytokine, suppresses the response of murine bone-marrow-derived conventional dendritic cells (cDCs) and splenic DCs to Type I interferons (IFNs). Here, we an...

Alternative Titles

Full title

IL-4 Suppresses the Responses to TLR7 and TLR9 Stimulation and Increases the Permissiveness to Retroviral Infection of Murine Conventional Dendritic Cells

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Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1492542210

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1492542210

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0087668

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