Impact of ABCB1 and CYP2B6 Genetic Polymorphisms on Methadone Metabolism, Dose and Treatment Respons...
Impact of ABCB1 and CYP2B6 Genetic Polymorphisms on Methadone Metabolism, Dose and Treatment Response in Patients with Opioid Addiction: A Systematic Review and Meta-Analysis
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Contents
Genetic variability may influence methadone metabolism, dose requirements, and risk of relapse.
To determine whether the CYP2B6*6 or ABCB1 (rs1045642) polymorphisms are associated with variation in methadone response (plasma concentration, dose, or response to treatment).
Two independent reviewers searched Medline, EMBASE, CINAHL, PsycINFO, a...
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Full title
Impact of ABCB1 and CYP2B6 Genetic Polymorphisms on Methadone Metabolism, Dose and Treatment Response in Patients with Opioid Addiction: A Systematic Review and Meta-Analysis
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TN_cdi_plos_journals_1492542215
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1492542215
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0086114
