Phosphoenolpyruvate carboxylase identified as a key enzyme in erythrocytic Plasmodium falciparum car...
Phosphoenolpyruvate carboxylase identified as a key enzyme in erythrocytic Plasmodium falciparum carbon metabolism
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Phospoenolpyruvate carboxylase (PEPC) is absent from humans but encoded in the Plasmodium falciparum genome, suggesting that PEPC has a parasite-specific function. To investigate its importance in P. falciparum, we generated a pepc null mutant (D10(Δpepc) ), which was only achievable when malate, a reduction product of oxaloacetate, was added to th...
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Phosphoenolpyruvate carboxylase identified as a key enzyme in erythrocytic Plasmodium falciparum carbon metabolism
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TN_cdi_plos_journals_1498392699
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1498392699
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1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1003876
