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Extracellular Zinc Competitively Inhibits Manganese Uptake and Compromises Oxidative Stress Manageme...

Extracellular Zinc Competitively Inhibits Manganese Uptake and Compromises Oxidative Stress Manageme...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1499826532

Extracellular Zinc Competitively Inhibits Manganese Uptake and Compromises Oxidative Stress Management in Streptococcus pneumoniae

About this item

Full title

Extracellular Zinc Competitively Inhibits Manganese Uptake and Compromises Oxidative Stress Management in Streptococcus pneumoniae

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-02, Vol.9 (2), p.e89427

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Streptococcus pneumoniae requires manganese for colonization of the human host, but the underlying molecular basis for this requirement has not been elucidated. Recently, it was shown that zinc could compromise manganese uptake and that zinc levels increased during infection by S. pneumoniae in all the niches that it colonized. Here we show, by qua...

Alternative Titles

Full title

Extracellular Zinc Competitively Inhibits Manganese Uptake and Compromises Oxidative Stress Management in Streptococcus pneumoniae

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1499826532

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1499826532

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0089427

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