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Measuring cytotoxicity by bioluminescence imaging outperforms the standard chromium-51 release assay

Measuring cytotoxicity by bioluminescence imaging outperforms the standard chromium-51 release assay

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1500409896

Measuring cytotoxicity by bioluminescence imaging outperforms the standard chromium-51 release assay

About this item

Full title

Measuring cytotoxicity by bioluminescence imaging outperforms the standard chromium-51 release assay

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-02, Vol.9 (2), p.e89357

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The chromium-release assay developed in 1968 is still the most commonly used method to measure cytotoxicity by T cells and by natural killer cells. Target cells are loaded in vitro with radioactive chromium and lysis is determined by measuring chromium in the supernatant released by dying cells. Since then, alternative methods have been developed u...

Alternative Titles

Full title

Measuring cytotoxicity by bioluminescence imaging outperforms the standard chromium-51 release assay

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1500409896

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1500409896

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0089357

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