Positive Regulation of TRAF6-Dependent Innate Immune Responses by Protein Phosphatase PP1-γ
Positive Regulation of TRAF6-Dependent Innate Immune Responses by Protein Phosphatase PP1-γ
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Innate immune sensors such as Toll-like receptors (TLRs) differentially utilize adaptor proteins and additional molecular mediators to ensure robust and precise immune responses to pathogen challenge. Through a gain-of-function genetic screen, we identified the gamma catalytic subunit of protein phosphatase 1 (PP1-γ) as a positive regulator of MyD8...
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Full title
Positive Regulation of TRAF6-Dependent Innate Immune Responses by Protein Phosphatase PP1-γ
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TN_cdi_plos_journals_1500751947
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1500751947
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0089284
