The antidepressant trans-2-phenylcyclopropylamine protects mice from high-fat-diet-induced obesity
The antidepressant trans-2-phenylcyclopropylamine protects mice from high-fat-diet-induced obesity
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Mice treated with the antidepressant trans-2-phenylcyclopropylamine (2-PCPA) were protected against diet-induced-obesity, and adiposity was reversed in pre-established diet-induced obese mice. Contrary to a recent report that inhibition of lysine-specific demethylase-1 by 2-PCPA results in increased energy expenditure, long-term 2-PCPA treatment ha...
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Full title
The antidepressant trans-2-phenylcyclopropylamine protects mice from high-fat-diet-induced obesity
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TN_cdi_plos_journals_1500940056
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1500940056
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0089199
