Absence of Cardiovascular Manifestations in a Haploinsufficient Tgfbr1 Mouse Model
Absence of Cardiovascular Manifestations in a Haploinsufficient Tgfbr1 Mouse Model
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Author / Creator
Renard, Marjolijn , Trachet, Bram , Casteleyn, Christophe , Campens, Laurence , Cornillie, Pieter , Callewaert, Bert , Deleye, Steven , Vandeghinste, Bert , van Heijningen, Paula M. , Dietz, Harry , De Vos, Filip , Essers, Jeroen , Staelens, Steven , Segers, Patrick , Loeys, Bart , Coucke, Paul , De Paepe, Anne and De Backer, Julie
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Loeys-Dietz syndrome (LDS) is an autosomal dominant arterial aneurysm disease belonging to the spectrum of transforming growth factor β (TGFβ)-associated vasculopathies. In its most typical form it is characterized by the presence of hypertelorism, bifid uvula/cleft palate and aortic aneurysm and/or arterial tortuosity. LDS is caused by heterozygou...
Alternative Titles
Full title
Absence of Cardiovascular Manifestations in a Haploinsufficient Tgfbr1 Mouse Model
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Record Identifier
TN_cdi_plos_journals_1501614052
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1501614052
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0089749
