Suppression of Immunodominant Antitumor and Antiviral CD8+ T Cell Responses by Indoleamine 2,3-Dioxy...
Suppression of Immunodominant Antitumor and Antiviral CD8+ T Cell Responses by Indoleamine 2,3-Dioxygenase
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Publisher
United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Indoleamine 2,3-dioxygenase (IDO) is a tryptophan-degrading enzyme known to suppress antitumor CD8(+) T cells (TCD8). The role of IDO in regulation of antiviral TCD8 responses is far less clear. In addition, whether IDO controls both immunodominant and subdominant TCD8 is not fully understood. This is an important question because the dominance sta...
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Full title
Suppression of Immunodominant Antitumor and Antiviral CD8+ T Cell Responses by Indoleamine 2,3-Dioxygenase
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TN_cdi_plos_journals_1503271616
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1503271616
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0090439
