Loss of Polycystin-1 Inhibits Bicc1 Expression during Mouse Development
Loss of Polycystin-1 Inhibits Bicc1 Expression during Mouse Development
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Author / Creator
Lian, Peiwen , Li, Ao , Li, Yuan , Liu, Haichao , Liang, Dan , Hu, Bo , Lin, De , Jiang, Tang , Moeckel, Gilbert , Qin, Dahui and Wu, Guanqing
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Bicc1 is a mouse homologue of Drosophila Bicaudal-C (dBic-C), which encodes an RNA-binding protein. Orthologs of dBic-C have been identified in many species, from C. elegans to humans. Bicc1-mutant mice exhibit a cystic phenotype in the kidney that is very similar to human polycystic kidney disease. Even though many studies have explored the gene c...
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Full title
Loss of Polycystin-1 Inhibits Bicc1 Expression during Mouse Development
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TN_cdi_plos_journals_1503771897
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1503771897
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0088816
