Design rules for selective binding of nuclear localization signals to minor site of importin α
Design rules for selective binding of nuclear localization signals to minor site of importin α
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Selectivity is a critical issue in molecular recognition. However, design rules that underlie selectivity are often not well understood. Here, we studied five classical nuclear localization signals (NLSs) that contain the motif KRx(W/F/Y)xxAF and selectively bind to the minor site of importin α. The selectivity for the minor site is dissected by bu...
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Design rules for selective binding of nuclear localization signals to minor site of importin α
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TN_cdi_plos_journals_1504978446
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1504978446
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0091025
