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Overexpression of WRAP53 Is Associated with Development and Progression of Esophageal Squamous Cell...

Overexpression of WRAP53 Is Associated with Development and Progression of Esophageal Squamous Cell...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1507246945

Overexpression of WRAP53 Is Associated with Development and Progression of Esophageal Squamous Cell Carcinoma

About this item

Full title

Overexpression of WRAP53 Is Associated with Development and Progression of Esophageal Squamous Cell Carcinoma

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-03, Vol.9 (3), p.e91670

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Esophageal squamous cell carcinoma (ESCC) is a highly aggressive cancer whose underlying molecular mechanisms are poorly understood. The natural antisense transcript (NAT) WRAP53 regulates p53 expression and WRAP53 protein is a component of telomerase. NATs play key roles in carcinogenesis, and although WRAP53 is known to increase cancer cell survi...

Alternative Titles

Full title

Overexpression of WRAP53 Is Associated with Development and Progression of Esophageal Squamous Cell Carcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1507246945

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1507246945

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0091670

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