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Comparative RNAi Screens in C. elegans and C. briggsae Reveal the Impact of Developmental System Dri...

Comparative RNAi Screens in C. elegans and C. briggsae Reveal the Impact of Developmental System Dri...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1507833796

Comparative RNAi Screens in C. elegans and C. briggsae Reveal the Impact of Developmental System Drift on Gene Function

About this item

Full title

Comparative RNAi Screens in C. elegans and C. briggsae Reveal the Impact of Developmental System Drift on Gene Function

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2014-02, Vol.10 (2), p.e1004077

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Although two related species may have extremely similar phenotypes, the genetic networks underpinning this conserved biology may have diverged substantially since they last shared a common ancestor. This is termed Developmental System Drift (DSD) and reflects the plasticity of genetic networks. One consequence of DSD is that some orthologous genes...

Alternative Titles

Full title

Comparative RNAi Screens in C. elegans and C. briggsae Reveal the Impact of Developmental System Drift on Gene Function

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1507833796

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1507833796

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1004077

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