Natural Polymorphisms in Tap2 Influence Negative Selection and CD4∶CD8 Lineage Commitment in the Rat
Natural Polymorphisms in Tap2 Influence Negative Selection and CD4∶CD8 Lineage Commitment in the Rat
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Author / Creator
EURATRANS Consortium , Tuncel, Jonatan , Haag, Sabrina , Yau, Anthony C. Y. , Norin, Ulrika , Baud, Amelie , Lönnblom, Erik , Maratou, Klio , Ytterberg, A. Jimmy , Ekman, Diana , Thordardottir, Soley , Johannesson, Martina , Gillett, Alan , Stridh, Pernilla , Jagodic, Maja , Olsson, Tomas , Fernández-Teruel, Alberto , Zubarev, Roman A. , Mott, Richard , Aitman, Timothy J. , Flint, Jonathan and Holmdahl, Rikard
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Genetic variation in the major histocompatibility complex (MHC) affects CD4∶CD8 lineage commitment and MHC expression. However, the contribution of specific genes in this gene-dense region has not yet been resolved. Nor has it been established whether the same genes regulate MHC expression and T cell selection. Here, we assessed the impact of natur...
Alternative Titles
Full title
Natural Polymorphisms in Tap2 Influence Negative Selection and CD4∶CD8 Lineage Commitment in the Rat
Authors, Artists and Contributors
Author / Creator
Tuncel, Jonatan
Haag, Sabrina
Yau, Anthony C. Y.
Norin, Ulrika
Baud, Amelie
Lönnblom, Erik
Maratou, Klio
Ytterberg, A. Jimmy
Ekman, Diana
Thordardottir, Soley
Johannesson, Martina
Gillett, Alan
Stridh, Pernilla
Jagodic, Maja
Olsson, Tomas
Fernández-Teruel, Alberto
Zubarev, Roman A.
Mott, Richard
Aitman, Timothy J.
Flint, Jonathan
Holmdahl, Rikard
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Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1507833887
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1507833887
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1004151
