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Extreme Population Differences in the Human Zinc Transporter ZIP4 (SLC39A4) Are Explained by Positiv...

Extreme Population Differences in the Human Zinc Transporter ZIP4 (SLC39A4) Are Explained by Positiv...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1507833890

Extreme Population Differences in the Human Zinc Transporter ZIP4 (SLC39A4) Are Explained by Positive Selection in Sub-Saharan Africa

About this item

Full title

Extreme Population Differences in the Human Zinc Transporter ZIP4 (SLC39A4) Are Explained by Positive Selection in Sub-Saharan Africa

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2014-02, Vol.10 (2), p.e1004128-e1004128

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Extreme differences in allele frequency between West Africans and Eurasians were observed for a leucine-to-valine substitution (Leu372Val) in the human intestinal zinc uptake transporter, ZIP4, yet no further evidence was found for a selective sweep around the ZIP4 gene (SLC39A4). By interrogating allele frequencies in more than 100 diverse human p...

Alternative Titles

Full title

Extreme Population Differences in the Human Zinc Transporter ZIP4 (SLC39A4) Are Explained by Positive Selection in Sub-Saharan Africa

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1507833890

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1507833890

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1004128

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