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Interleukin-6 modulation of intestinal epithelial tight junction permeability is mediated by JNK pat...

Interleukin-6 modulation of intestinal epithelial tight junction permeability is mediated by JNK pat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1509660057

Interleukin-6 modulation of intestinal epithelial tight junction permeability is mediated by JNK pathway activation of claudin-2 gene

About this item

Full title

Interleukin-6 modulation of intestinal epithelial tight junction permeability is mediated by JNK pathway activation of claudin-2 gene

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-03, Vol.9 (3), p.e85345

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Defective intestinal epithelial tight junction (TJ) barrier has been shown to be a pathogenic factor in the development of intestinal inflammation. Interleukin-6 (IL-6) is a pleiotropic, pro-inflammatory cytokine which plays an important role in promoting inflammatory response in the gut and in the systemic circulation. Despite its key role in medi...

Alternative Titles

Full title

Interleukin-6 modulation of intestinal epithelial tight junction permeability is mediated by JNK pathway activation of claudin-2 gene

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1509660057

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1509660057

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0085345

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