Monocrotophos Induces the Expression and Activity of Xenobiotic Metabolizing Enzymes in Pre-Sensitiz...
Monocrotophos Induces the Expression and Activity of Xenobiotic Metabolizing Enzymes in Pre-Sensitized Cultured Human Brain Cells
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The expression and metabolic profile of cytochrome P450s (CYPs) is largely missing in human brain due to non-availability of brain tissue. We attempted to address the issue by using human brain neuronal (SH-SY5Y) and glial (U373-MG) cells. The expression and activity of CYP1A1, 2B6 and 2E1 were carried out in the cells exposed to CYP inducers viz.,...
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Monocrotophos Induces the Expression and Activity of Xenobiotic Metabolizing Enzymes in Pre-Sensitized Cultured Human Brain Cells
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TN_cdi_plos_journals_1509660089
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1509660089
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0091946
