Endoplasmic Reticulum Stress-Mediated Activation of p38 MAPK, Caspase-2 and Caspase-8 Leads to Abrin...
Endoplasmic Reticulum Stress-Mediated Activation of p38 MAPK, Caspase-2 and Caspase-8 Leads to Abrin-Induced Apoptosis
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Abrin from Abrus precatorius plant is a potent protein synthesis inhibitor and induces apoptosis in cells. However, the relationship between inhibition of protein synthesis and apoptosis is not well understood. Inhibition of protein synthesis by abrin can lead to accumulation of unfolded protein in the endoplasmic reticulum causing ER stress. The o...
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Full title
Endoplasmic Reticulum Stress-Mediated Activation of p38 MAPK, Caspase-2 and Caspase-8 Leads to Abrin-Induced Apoptosis
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TN_cdi_plos_journals_1509663657
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1509663657
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0092586
