Exogenous t-PA Administration Increases Hippocampal Mature BDNF Levels. Plasmin- or NMDA-Dependent M...
Exogenous t-PA Administration Increases Hippocampal Mature BDNF Levels. Plasmin- or NMDA-Dependent Mechanism?
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Brain-derived neurotrophic factor (BDNF) through TrkB activation is central for brain functioning. Since the demonstration that plasmin is able to process pro-BDNF to mature BDNF and that these two forms have opposite effects on neuronal survival and plasticity, a particular attention has been paid to the link between tissue plasminogen activator (...
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Full title
Exogenous t-PA Administration Increases Hippocampal Mature BDNF Levels. Plasmin- or NMDA-Dependent Mechanism?
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TN_cdi_plos_journals_1510500387
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1510500387
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0092416
