Overexpression of miR-125a in myelodysplastic syndrome CD34+ cells modulates NF-κB activation and en...
Overexpression of miR-125a in myelodysplastic syndrome CD34+ cells modulates NF-κB activation and enhances erythroid differentiation arrest
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Myelodysplastic syndromes (MDS) are characterized by impaired proliferation and differentiation of hematopoietic stem cells. The participation of toll-like receptor (TLR)-mediated signaling in MDS is well documented. Increased TLR signaling leads to the constitutive activation of NF-κB, which mediates inflammation, cell proliferation and apoptosis....
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Overexpression of miR-125a in myelodysplastic syndrome CD34+ cells modulates NF-κB activation and enhances erythroid differentiation arrest
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TN_cdi_plos_journals_1511847970
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1511847970
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0093404
