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Remodeling of aorta extracellular matrix as a result of transient high oxygen exposure in newborn ra...

Remodeling of aorta extracellular matrix as a result of transient high oxygen exposure in newborn ra...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1517441578

Remodeling of aorta extracellular matrix as a result of transient high oxygen exposure in newborn rats: implication for arterial rigidity and hypertension risk

About this item

Full title

Remodeling of aorta extracellular matrix as a result of transient high oxygen exposure in newborn rats: implication for arterial rigidity and hypertension risk

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-04, Vol.9 (4), p.e92287

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Neonatal high-oxygen exposure leads to elevated blood pressure, microvascular rarefaction, vascular dysfunction and arterial (aorta) rigidity in adult rats. Whether structural changes are present in the matrix of aorta wall is unknown. Considering that elastin synthesis peaks in late fetal life in humans, and early postnatal life in rodents, we pos...

Alternative Titles

Full title

Remodeling of aorta extracellular matrix as a result of transient high oxygen exposure in newborn rats: implication for arterial rigidity and hypertension risk

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1517441578

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1517441578

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0092287

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