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SRA regulates adipogenesis by modulating p38/JNK phosphorylation and stimulating insulin receptor ge...

SRA regulates adipogenesis by modulating p38/JNK phosphorylation and stimulating insulin receptor ge...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1517445184

SRA regulates adipogenesis by modulating p38/JNK phosphorylation and stimulating insulin receptor gene expression and downstream signaling

About this item

Full title

SRA regulates adipogenesis by modulating p38/JNK phosphorylation and stimulating insulin receptor gene expression and downstream signaling

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-04, Vol.9 (4), p.e95416-e95416

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The Steroid Receptor RNA Activator (SRA) enhances adipogenesis and increases both glucose uptake and phosphorylation of Akt and FOXO1 in response to insulin. To assess the mechanism, we differentiated ST2 mesenchymal precursor cells that did or did not overexpress SRA into adipocytes using combinations of methylisobutylxanthine, dexamethasone and i...

Alternative Titles

Full title

SRA regulates adipogenesis by modulating p38/JNK phosphorylation and stimulating insulin receptor gene expression and downstream signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1517445184

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1517445184

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0095416

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