SRA regulates adipogenesis by modulating p38/JNK phosphorylation and stimulating insulin receptor ge...
SRA regulates adipogenesis by modulating p38/JNK phosphorylation and stimulating insulin receptor gene expression and downstream signaling
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The Steroid Receptor RNA Activator (SRA) enhances adipogenesis and increases both glucose uptake and phosphorylation of Akt and FOXO1 in response to insulin. To assess the mechanism, we differentiated ST2 mesenchymal precursor cells that did or did not overexpress SRA into adipocytes using combinations of methylisobutylxanthine, dexamethasone and i...
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Full title
SRA regulates adipogenesis by modulating p38/JNK phosphorylation and stimulating insulin receptor gene expression and downstream signaling
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TN_cdi_plos_journals_1517445184
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1517445184
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0095416