Characterization of a novel single-chain bispecific antibody for retargeting of T cells to tumor cel...
Characterization of a novel single-chain bispecific antibody for retargeting of T cells to tumor cells via the TCR co-receptor CD8
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
There is currently growing interest in retargeting of effector T cells to tumor cells via bispecific antibodies (bsAbs). Usually, bsAbs are directed on the one hand to the CD3 complex of T cells and on the other hand to a molecule expressed on the surface of the target cell. A bsAb-mediated cross-linkage via CD3 leads to an activation of CD8+ T cel...
Alternative Titles
Full title
Characterization of a novel single-chain bispecific antibody for retargeting of T cells to tumor cells via the TCR co-receptor CD8
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TN_cdi_plos_journals_1518097030
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1518097030
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0095517
