RCAN1 Overexpression Exacerbates Calcium Overloading-Induced Neuronal Apoptosis
RCAN1 Overexpression Exacerbates Calcium Overloading-Induced Neuronal Apoptosis
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Down Syndrome (DS) patients develop characteristic Alzheimer's Disease (AD) neuropathology after their middle age. Prominent neuronal loss has been observed in the cortical regions of AD brains. However, the underlying mechanism leading to this neuronal loss in both DS and AD remains to be elucidated. Calcium overloading and oxidative stress have b...
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RCAN1 Overexpression Exacerbates Calcium Overloading-Induced Neuronal Apoptosis
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TN_cdi_plos_journals_1518097219
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1518097219
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0095471