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RCAN1 Overexpression Exacerbates Calcium Overloading-Induced Neuronal Apoptosis

RCAN1 Overexpression Exacerbates Calcium Overloading-Induced Neuronal Apoptosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1518097219

RCAN1 Overexpression Exacerbates Calcium Overloading-Induced Neuronal Apoptosis

About this item

Full title

RCAN1 Overexpression Exacerbates Calcium Overloading-Induced Neuronal Apoptosis

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-04, Vol.9 (4), p.e95471

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Down Syndrome (DS) patients develop characteristic Alzheimer's Disease (AD) neuropathology after their middle age. Prominent neuronal loss has been observed in the cortical regions of AD brains. However, the underlying mechanism leading to this neuronal loss in both DS and AD remains to be elucidated. Calcium overloading and oxidative stress have b...

Alternative Titles

Full title

RCAN1 Overexpression Exacerbates Calcium Overloading-Induced Neuronal Apoptosis

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1518097219

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1518097219

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0095471

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