Direct angiotensin AT2 receptor stimulation using a novel AT2 receptor agonist, compound 21, evokes...
Direct angiotensin AT2 receptor stimulation using a novel AT2 receptor agonist, compound 21, evokes neuroprotection in conscious hypertensive rats
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United States: Public Library of Science
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English
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United States: Public Library of Science
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In this study, the neuroprotective effect of a novel nonpeptide AT2R agonist, C21, was examined in a conscious model of stroke to verify a class effect of AT2R agonists as neuroprotective agents.
Spontaneously hypertensive rats (SHR) were pre-treated for 5 days prior to stroke with C21 alone or in combination with the AT2R antagonist PD123319. I...
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Full title
Direct angiotensin AT2 receptor stimulation using a novel AT2 receptor agonist, compound 21, evokes neuroprotection in conscious hypertensive rats
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TN_cdi_plos_journals_1518097339
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1518097339
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0095762
