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Sub-inhibitory fosmidomycin exposures elicits oxidative stress in Salmonella enterica serovar Typhim...

Sub-inhibitory fosmidomycin exposures elicits oxidative stress in Salmonella enterica serovar Typhim...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1518097438

Sub-inhibitory fosmidomycin exposures elicits oxidative stress in Salmonella enterica serovar Typhimurium LT2

About this item

Full title

Sub-inhibitory fosmidomycin exposures elicits oxidative stress in Salmonella enterica serovar Typhimurium LT2

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-04, Vol.9 (4), p.e95271

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Fosmidomycin is a time-dependent nanomolar inhibitor of methylerythritol phosphate (MEP) synthase, which is the enzyme that catalyzes the first committed step in the MEP pathway to isoprenoids. Importantly, fosmidomycin is one of only a few MEP pathway-specific inhibitors that exhibits antimicrobial activity. Most inhibitors identified to date only...

Alternative Titles

Full title

Sub-inhibitory fosmidomycin exposures elicits oxidative stress in Salmonella enterica serovar Typhimurium LT2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1518097438

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1518097438

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0095271

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