Enhanced antitumor efficacy of an oncolytic herpes simplex virus expressing an endostatin-angiostati...
Enhanced antitumor efficacy of an oncolytic herpes simplex virus expressing an endostatin-angiostatin fusion gene in human glioblastoma stem cell xenografts
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Viruses have demonstrated strong potential for the therapeutic targeting of glioblastoma stem cells (GSCs). In this study, the use of a herpes simplex virus carrying endostatin-angiostatin (VAE) as a novel therapeutic targeting strategy for glioblastoma-derived cancer stem cells was investigated. We isolated six stable GSC-enriched cultures from 36...
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Enhanced antitumor efficacy of an oncolytic herpes simplex virus expressing an endostatin-angiostatin fusion gene in human glioblastoma stem cell xenografts
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TN_cdi_plos_journals_1518469893
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1518469893
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0095872
