Does KRAS Testing in Metastatic Colorectal Cancer Impact Overall Survival? A Comparative Effectivene...
Does KRAS Testing in Metastatic Colorectal Cancer Impact Overall Survival? A Comparative Effectiveness Study in a Population-Based Sample
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Full title
Author / Creator
Feigelson, Heather Spencer , Zeng, Chan , Pawloski, Pamala A. , Onitilo, Adedayo A. , Richards, C. Sue , Johnson, Monique A. , Kauffman, Tia L. , Webster, Jennifer , Nyirenda, Carsie , Alexander, Gwen L. , Hwang, Clara , Cross, Deanna , McCarty, Catherine A. , Davis, Robert L. , Schwarzkopf, Denise , Williams, Andrew E. , Honda, Stacey , Daida, Yihe , Kushi, Lawrence H. , Delate, Thomas , Goddard, Katrina A. B. , on behalf of the CERGEN Study Team and CERGEN Study Team
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Epidermal growth factor receptor (EGFR) inhibitors are approved for treating metastatic colorectal cancer (CRC); KRAS mutation testing is recommended prior to treatment. We conducted a non-inferiority analysis to examine whether KRAS testing has impacted survival in CRC patients.
We included 1186 metastatic CRC cases from seven health plans. A c...
Alternative Titles
Full title
Does KRAS Testing in Metastatic Colorectal Cancer Impact Overall Survival? A Comparative Effectiveness Study in a Population-Based Sample
Authors, Artists and Contributors
Author / Creator
Zeng, Chan
Pawloski, Pamala A.
Onitilo, Adedayo A.
Richards, C. Sue
Johnson, Monique A.
Kauffman, Tia L.
Webster, Jennifer
Nyirenda, Carsie
Alexander, Gwen L.
Hwang, Clara
Cross, Deanna
McCarty, Catherine A.
Davis, Robert L.
Schwarzkopf, Denise
Williams, Andrew E.
Honda, Stacey
Daida, Yihe
Kushi, Lawrence H.
Delate, Thomas
Goddard, Katrina A. B.
on behalf of the CERGEN Study Team
CERGEN Study Team
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1520401677
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1520401677
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0094977
