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The Transcription Factor EGR1 Localizes to the Nucleolus and Is Linked to Suppression of Ribosomal P...

The Transcription Factor EGR1 Localizes to the Nucleolus and Is Linked to Suppression of Ribosomal P...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1520401765

The Transcription Factor EGR1 Localizes to the Nucleolus and Is Linked to Suppression of Ribosomal Precursor Synthesis

About this item

Full title

The Transcription Factor EGR1 Localizes to the Nucleolus and Is Linked to Suppression of Ribosomal Precursor Synthesis

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-05, Vol.9 (5), p.e96037-e96037

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

EGR1 is an immediate early gene with a wide range of activities as transcription factor, spanning from regulation of cell growth to differentiation. Numerous studies show that EGR1 either promotes the proliferation of stimulated cells or suppresses the tumorigenic growth of transformed cells. Upon interaction with ARF, EGR1 is sumoylated and acquir...

Alternative Titles

Full title

The Transcription Factor EGR1 Localizes to the Nucleolus and Is Linked to Suppression of Ribosomal Precursor Synthesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1520401765

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1520401765

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0096037

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