Mouse Spermatocytes Express CYP2E1 and Respond to Acrylamide Exposure
Mouse Spermatocytes Express CYP2E1 and Respond to Acrylamide Exposure
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Metabolism of xenobiotics by cytochrome P450s (encoded by the CYP genes) often leads to bio-activation, producing reactive metabolites that interfere with cellular processes and cause DNA damage. In the testes, DNA damage induced by xenobiotics has been associated with impaired spermatogenesis and adverse effects on reproductive health. We previous...
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Full title
Mouse Spermatocytes Express CYP2E1 and Respond to Acrylamide Exposure
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TN_cdi_plos_journals_1520572096
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1520572096
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0094904
