Loss of central auditory processing in a mouse model of Canavan disease
Loss of central auditory processing in a mouse model of Canavan disease
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Canavan Disease (CD) is a leukodystrophy caused by homozygous null mutations in the gene encoding aspartoacylase (ASPA). ASPA-deficiency is characterized by severe psychomotor retardation, and excessive levels of the ASPA substrate N-acetylaspartate (NAA). ASPA is an oligodendrocyte marker and it is believed that CD has a central etiology. However,...
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Full title
Loss of central auditory processing in a mouse model of Canavan disease
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TN_cdi_plos_journals_1524628184
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1524628184
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0097374
