Exposure-Dependent Control of Malaria-Induced Inflammation in Children
Exposure-Dependent Control of Malaria-Induced Inflammation in Children
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Author / Creator
Portugal, Silvia , Moebius, Jacqueline , Skinner, Jeff , Doumbo, Safiatou , Doumtabe, Didier , Kone, Younoussou , Dia, Seydou , Kanakabandi, Kishore , Sturdevant, Daniel E. , Virtaneva, Kimmo , Porcella, Stephen F. , Li, Shanping , Doumbo, Ogobara K. , Kayentao, Kassoum , Ongoiba, Aissata , Traore, Boubacar and Crompton, Peter D.
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
In malaria-naïve individuals, Plasmodium falciparum infection results in high levels of parasite-infected red blood cells (iRBCs) that trigger systemic inflammation and fever. Conversely, individuals in endemic areas who are repeatedly infected are often asymptomatic and have low levels of iRBCs, even young children. We hypothesized that febrile ma...
Alternative Titles
Full title
Exposure-Dependent Control of Malaria-Induced Inflammation in Children
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Author / Creator
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Record Identifier
TN_cdi_plos_journals_1525297300
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1525297300
Other Identifiers
ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1004079
