Mutations in conserved residues of the C. elegans microRNA Argonaute ALG-1 identify separable functi...
Mutations in conserved residues of the C. elegans microRNA Argonaute ALG-1 identify separable functions in ALG-1 miRISC loading and target repression
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United States: Public Library of Science
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English
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United States: Public Library of Science
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microRNAs function in diverse developmental and physiological processes by regulating target gene expression at the post-transcriptional level. ALG-1 is one of two Caenorhabditis elegans Argonautes (ALG-1 and ALG-2) that together are essential for microRNA biogenesis and function. Here, we report the identification of novel antimorphic (anti) allel...
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Mutations in conserved residues of the C. elegans microRNA Argonaute ALG-1 identify separable functions in ALG-1 miRISC loading and target repression
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TN_cdi_plos_journals_1525304306
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1525304306
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1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1004286
