Mycobacterium tuberculosis Multidrug Resistant Strain M Induces an Altered Activation of Cytotoxic C...
Mycobacterium tuberculosis Multidrug Resistant Strain M Induces an Altered Activation of Cytotoxic CD8+ T Cells
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
In human tuberculosis (TB), CD8+ T cells contribute to host defense by the release of Th1 cytokines and the direct killing of Mycobacterium tuberculosis (Mtb)-infected macrophages via granule exocytosis pathway or the engagement of receptors on target cells. Previously we demonstrated that strain M, the most prevalent multidrug-resistant (MDR) Mtb...
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Full title
Mycobacterium tuberculosis Multidrug Resistant Strain M Induces an Altered Activation of Cytotoxic CD8+ T Cells
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TN_cdi_plos_journals_1525343037
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1525343037
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0097837
