Identification of T. gondii Myosin Light Chain-1 as a Direct Target of TachypleginA-2, a Small-Molec...
Identification of T. gondii Myosin Light Chain-1 as a Direct Target of TachypleginA-2, a Small-Molecule Inhibitor of Parasite Motility and Invasion
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Motility of the protozoan parasite Toxoplasma gondii plays an important role in the parasite's life cycle and virulence within animal and human hosts. Motility is driven by a myosin motor complex that is highly conserved across the Phylum Apicomplexa. Two key components of this complex are the class XIV unconventional myosin, TgMyoA, and its associ...
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Full title
Identification of T. gondii Myosin Light Chain-1 as a Direct Target of TachypleginA-2, a Small-Molecule Inhibitor of Parasite Motility and Invasion
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TN_cdi_plos_journals_1531988237
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1531988237
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0098056