Role of Na,K-ATPase α1 and α2 Isoforms in the Support of Astrocyte Glutamate Uptake
Role of Na,K-ATPase α1 and α2 Isoforms in the Support of Astrocyte Glutamate Uptake
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Contents
Glutamate released during neuronal activity is cleared from the synaptic space via the astrocytic glutamate/Na(+) co-transporters. This transport is driven by the transmembrane Na(+) gradient mediated by Na,K-ATPase. Astrocytes express two isoforms of the catalytic Na,K-ATPase α subunits; the ubiquitously expressed α1 subunit and the α2 subunit tha...
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Full title
Role of Na,K-ATPase α1 and α2 Isoforms in the Support of Astrocyte Glutamate Uptake
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TN_cdi_plos_journals_1532987229
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1532987229
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0098469
