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The Subfamily-Specific Interaction between Kv2.1 and Kv6.4 Subunits Is Determined by Interactions be...

The Subfamily-Specific Interaction between Kv2.1 and Kv6.4 Subunits Is Determined by Interactions be...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1532987416

The Subfamily-Specific Interaction between Kv2.1 and Kv6.4 Subunits Is Determined by Interactions between the N- and C-termini

About this item

Full title

The Subfamily-Specific Interaction between Kv2.1 and Kv6.4 Subunits Is Determined by Interactions between the N- and C-termini

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-06, Vol.9 (6), p.e98960

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The "silent" voltage-gated potassium (KvS) channel subunit Kv6.4 does not form electrically functional homotetramers at the plasma membrane but assembles with Kv2.1 subunits, generating functional Kv2.1/Kv6.4 heterotetramers. The N-terminal T1 domain determines the subfamily-specific assembly of Kv1-4 subunits by preventing interactions between sub...

Alternative Titles

Full title

The Subfamily-Specific Interaction between Kv2.1 and Kv6.4 Subunits Is Determined by Interactions between the N- and C-termini

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1532987416

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1532987416

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0098960

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