Essential Plasticity and Redundancy of Metabolism Unveiled by Synthetic Lethality Analysis
Essential Plasticity and Redundancy of Metabolism Unveiled by Synthetic Lethality Analysis
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
We unravel how functional plasticity and redundancy are essential mechanisms underlying the ability to survive of metabolic networks. We perform an exhaustive computational screening of synthetic lethal reaction pairs in Escherichia coli in a minimal medium and we find that synthetic lethal pairs divide in two different groups depending on whether...
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Full title
Essential Plasticity and Redundancy of Metabolism Unveiled by Synthetic Lethality Analysis
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TN_cdi_plos_journals_1536043429
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1536043429
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ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1003637
