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CoCl2, a Mimic of Hypoxia, Induces Formation of Polyploid Giant Cells with Stem Characteristics in C...

CoCl2, a Mimic of Hypoxia, Induces Formation of Polyploid Giant Cells with Stem Characteristics in C...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1536089407

CoCl2, a Mimic of Hypoxia, Induces Formation of Polyploid Giant Cells with Stem Characteristics in Colon Cancer

About this item

Full title

CoCl2, a Mimic of Hypoxia, Induces Formation of Polyploid Giant Cells with Stem Characteristics in Colon Cancer

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-06, Vol.9 (6), p.e99143

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The induction of polyploidy is considered the reproductive end of cells, but there is evidence that polyploid giant cancer cells (PGCCs) contribute to cell repopulation during tumor relapse. However, the role of these cells in the development, progression and response to therapy in colon cancer remains undefined. Therefore, the main objective of th...

Alternative Titles

Full title

CoCl2, a Mimic of Hypoxia, Induces Formation of Polyploid Giant Cells with Stem Characteristics in Colon Cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1536089407

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1536089407

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0099143

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