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High Levels of SOX5 Decrease Proliferative Capacity of Human B Cells, but Permit Plasmablast Differe...

High Levels of SOX5 Decrease Proliferative Capacity of Human B Cells, but Permit Plasmablast Differe...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1537651488

High Levels of SOX5 Decrease Proliferative Capacity of Human B Cells, but Permit Plasmablast Differentiation

About this item

Full title

High Levels of SOX5 Decrease Proliferative Capacity of Human B Cells, but Permit Plasmablast Differentiation

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-06, Vol.9 (6), p.e100328-e100328

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Currently very little is known about the differential expression and function of the transcription factor SOX5 during B cell maturation. We identified two new splice variants of SOX5 in human B cells, encoding the known L-SOX5B isoform and a new shorter isoform L-SOX5F. The SOX5 transcripts are highly expressed during late stages of B-cell differen...

Alternative Titles

Full title

High Levels of SOX5 Decrease Proliferative Capacity of Human B Cells, but Permit Plasmablast Differentiation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1537651488

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1537651488

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0100328

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