High Levels of SOX5 Decrease Proliferative Capacity of Human B Cells, but Permit Plasmablast Differe...
High Levels of SOX5 Decrease Proliferative Capacity of Human B Cells, but Permit Plasmablast Differentiation
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Author / Creator
Rakhmanov, Mirzokhid , Sic, Heiko , Kienzler, Anne-Kathrin , Fischer, Beate , Rizzi, Marta , Seidl, Maximilian , Melkaoui, Kerstina , Unger, Susanne , Moehle, Luisa , Schmit, Nadine E. , Deshmukh, Sachin D. , Ayata, Cemil Korcan , Schuh, Wolfgang , Zhang, Zhibing , Cosset, François-Loic , Verhoeyen, Els , Peter, Hans-Hartmut , Voll, Reinhard E. , Salzer, Ulrich , Eibel, Hermann and Warnatz, Klaus
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Currently very little is known about the differential expression and function of the transcription factor SOX5 during B cell maturation. We identified two new splice variants of SOX5 in human B cells, encoding the known L-SOX5B isoform and a new shorter isoform L-SOX5F. The SOX5 transcripts are highly expressed during late stages of B-cell differen...
Alternative Titles
Full title
High Levels of SOX5 Decrease Proliferative Capacity of Human B Cells, but Permit Plasmablast Differentiation
Authors, Artists and Contributors
Author / Creator
Sic, Heiko
Kienzler, Anne-Kathrin
Fischer, Beate
Rizzi, Marta
Seidl, Maximilian
Melkaoui, Kerstina
Unger, Susanne
Moehle, Luisa
Schmit, Nadine E.
Deshmukh, Sachin D.
Ayata, Cemil Korcan
Schuh, Wolfgang
Zhang, Zhibing
Cosset, François-Loic
Verhoeyen, Els
Peter, Hans-Hartmut
Voll, Reinhard E.
Salzer, Ulrich
Eibel, Hermann
Warnatz, Klaus
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Record Identifier
TN_cdi_plos_journals_1537651488
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1537651488
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0100328