Altered goblet cell differentiation and surface mucus properties in Hirschsprung disease
Altered goblet cell differentiation and surface mucus properties in Hirschsprung disease
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Hirschsprung disease-associated enterocolitis (HAEC) leads to significant mortality and morbidity, but its pathogenesis remains unknown. Changes in the colonic epithelium related to goblet cells and the luminal mucus layer have been postulated to play a key role. Here we show that the colonic epithelium of both aganglionic and ganglionic segments a...
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Full title
Altered goblet cell differentiation and surface mucus properties in Hirschsprung disease
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TN_cdi_plos_journals_1537651529
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1537651529
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0099944
