Key Role of the Endothelial TGF-β/ALK1/Endoglin Signaling Pathway in Humans and Rodents Pulmonary Hy...
Key Role of the Endothelial TGF-β/ALK1/Endoglin Signaling Pathway in Humans and Rodents Pulmonary Hypertension
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Mutations affecting transforming growth factor-beta (TGF-β) superfamily receptors, activin receptor-like kinase (ALK)-1, and endoglin (ENG) occur in patients with pulmonary arterial hypertension (PAH). To determine whether the TGF-β/ALK1/ENG pathway was involved in PAH, we investigated pulmonary TGF-β, ALK1, ALK5, and ENG expressions in human lung...
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Key Role of the Endothelial TGF-β/ALK1/Endoglin Signaling Pathway in Humans and Rodents Pulmonary Hypertension
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TN_cdi_plos_journals_1539494630
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1539494630
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0100310
