Structure-Based Prediction of Asparagine and Aspartate Degradation Sites in Antibody Variable Region...
Structure-Based Prediction of Asparagine and Aspartate Degradation Sites in Antibody Variable Regions
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Monoclonal antibodies (mAbs) and proteins containing antibody domains are the most prevalent class of biotherapeutics in diverse indication areas. Today, established techniques such as immunization or phage display allow for an efficient generation of new mAbs. Besides functional properties, the stability of future therapeutic mAbs is a key selecti...
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Full title
Structure-Based Prediction of Asparagine and Aspartate Degradation Sites in Antibody Variable Regions
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TN_cdi_plos_journals_1539751837
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1539751837
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0100736
