Fatty Acid Synthase Inhibitors Induce Apoptosis in Non-Tumorigenic Melan-A Cells Associated with Inh...
Fatty Acid Synthase Inhibitors Induce Apoptosis in Non-Tumorigenic Melan-A Cells Associated with Inhibition of Mitochondrial Respiration
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The metabolic enzyme fatty acid synthase (FASN) is responsible for the endogenous synthesis of palmitate, a saturated long-chain fatty acid. In contrast to most normal tissues, a variety of human cancers overexpress FASN. One such cancer is cutaneous melanoma, in which the level of FASN expression is associated with tumor invasion and poor prognosi...
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Fatty Acid Synthase Inhibitors Induce Apoptosis in Non-Tumorigenic Melan-A Cells Associated with Inhibition of Mitochondrial Respiration
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TN_cdi_plos_journals_1540471168
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1540471168
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0101060
