Single-Step Selection of Bivalent Aptamers Validated by Comparison with SELEX Using High-Throughput...
Single-Step Selection of Bivalent Aptamers Validated by Comparison with SELEX Using High-Throughput Sequencing
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The identification of nucleic acid aptamers would be advanced if they could be obtained after fewer rounds of selection and amplification. In this paper the identification of bivalent aptamers for thrombin by SELEX and single-step selection are compared using next generation sequencing and motif finding informatics. Results show that similar aptame...
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Single-Step Selection of Bivalent Aptamers Validated by Comparison with SELEX Using High-Throughput Sequencing
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TN_cdi_plos_journals_1540471318
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1540471318
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0100572
