Expression of the Genetic Suppressor Element 24.2 (GSE24.2) Decreases DNA Damage and Oxidative Stres...
Expression of the Genetic Suppressor Element 24.2 (GSE24.2) Decreases DNA Damage and Oxidative Stress in X-Linked Dyskeratosis Congenita Cells
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The predominant X-linked form of Dyskeratosis congenita results from mutations in DKC1, which encodes dyskerin, a protein required for ribosomal RNA modification that is also a component of the telomerase complex. We have previously found that expression of an internal fragment of dyskerin (GSE24.2) rescues telomerase activity in X-linked dyskerato...
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Expression of the Genetic Suppressor Element 24.2 (GSE24.2) Decreases DNA Damage and Oxidative Stress in X-Linked Dyskeratosis Congenita Cells
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TN_cdi_plos_journals_1543489213
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1543489213
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1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0101424
